Establishment of an avian leukosis virus subgroup A-resistant cell line
نویسندگان
چکیده
منابع مشابه
A novel subgroup of exogenous avian leukosis virus in chickens.
An avian leukosis virus with a wide host range belonging to a new subgroup for chickens was isolated from meat-type chicken lines. The virus, of which HPRS-103 strain is the prototype, was of low oncogenicity in chickens but appeared to behave like an exogenous leukosis virus. Neutralizing antibodies to the virus were found in three of five meat-type chicken lines, but not in seven layer lines....
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Subgroup J avian leukosis virus (ALV-J) is unique among the avian sarcoma and leukosis viruses in using the multimembrane-spanning cell surface protein Na(+)/H(+) exchanger type 1 (NHE1) as a receptor. The precise localization of amino acids critical for NHE1 receptor activity is key in understanding the virus-receptor interaction and potential interference with virus entry. Because no resistan...
متن کاملAvian Leukosis Virus Subgroup J in Layer Chickens, China
To the Editor: In recent years, cases of avian leukosis virus subgroup J (ALV-J) infection and tumors in commercial layer chickens and breeders of egg-type chickens have been emerging in the People’s Republic of China. ALV-J was fi rst isolated from meattype chickens with myeloid leukosis in 1988. Although egg-type chickens have been experimentally infected with ALV-J to induce tumors (1), fi e...
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The transcription factor Blimp-1 has emerged as a regulator of cell fate in embryonic (germ cell) and adult (Band T-cell immune effector and epithelial) lineages. It has also been proposed to act as a tumor suppressor in B-cell malignancy. Here, we present a novel in vivo system enabling the targeted genetic manipulation of cells expressing Prdm1, the gene encoding Blimp-1. We created bacterial...
متن کاملDevelopment of an avian leukosis-sarcoma virus subgroup A pseudotyped lentiviral vector.
We are using avian leukosis-sarcoma virus (ALSV) vectors to generate mouse tumor models in transgenic mice expressing TVA, the receptor for subgroup A ALSV. Like other classical retroviruses, ALSV requires cell division to establish a provirus after infection of host cells. In contrast, lentiviral vectors are capable of integrating their viral DNA into the genomes of nondividing cells. With the...
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ژورنال
عنوان ژورنال: Journal of Integrative Agriculture
سال: 2017
ISSN: 2095-3119
DOI: 10.1016/s2095-3119(16)61453-3